Since a lot of types of collagen have found their way on the market in recent years, which also raises numerous questions, it is not surprising that it is hard to choose the right one for yourself. For this reason we have prepared this Q&A on Medex collagen, which we hope will help you choose the right one.
How is the efficiency of collagen action being verified?
The efficiency of collagen is not verified with laboratory analyses, but rather with placebo controlled clinical studies on people. Our products contain only patented hydrolysed collagen the efficiency of which is proven by these studies.
Is the function of collagen based on subjective assessments of test subjects or assessors?
No. Clinical studies apply internationally recognised instrumental methods of analysis which are also applied in dermatology.
How is the content and size of peptides in collagen verified?
This cannot be determined with certainty with obsolete and inaccurate methods, such as the classic gel electrophoresis, but rather a standardised and validated HPSEC (high performance size exclusion chromatography) method is used with which the size and quantity of peptides can be accurately determined. Preparing a suitable sample is also important, since other components in the product can prevent detection later on.
Are input components of products also verified and controlled?
All input components are thoroughly analysed and confirmed only if they meet the specifications which ensure efficiency in accordance with clinical studies.
How much collagen has to be consumed to achieve the desired effects?
In order to achieve the effects it is necessary to take as much collagen as consumed by the test subjects in the clinical studies which prove the beneficial effect. This varies between different patented collagen, the beneficial effects are however generally visible when taking a daily dose of hydrolysed collagen from 2.5 g to 10 g regardless of its source (fish or bovine) or collagen source type (I, II or III).
Which patented components are contained in Medex collagen?
All our products contain exclusively patented collagen. In the products Kolagenlift in liquid 300 ml and Kolagenlift in powder 120 g we use the hydrolysed fish collagen Naticol®, in Kolagenlift in vials 10x9 ml we use the hydrolysed bovine collagen Verisol®, in Kolagen + vitamin C we use the hydrolysed bovine collagen Peptiplus®, and in Kolagenflex the hydrolysed bovine collagen Fortigel®. However, in Kolagen Q+ capsules we do not use hydrolysed collagen, but rather the native collagen Ovoderm® from eggshell membranes, which has a different mechanism of action, and the daily doses are therefore much lower (300 mg).
What size do particles of hydrolysed collagen have to be in order for it to have effect?
In most clinical studies, which have proven beneficial effects, hydrolysed collagen was used in the size ranging from 2 to 4 kDa (kilo Dalton). This is exactly the particle size of collagen in our products.
Is it true that larger collagen particles do not have an effect?
Clinical studies have not proven the level of efficiency of larger particles of hydrolysed collagen as of particles the size of 2 to 4 kDa. This is not true; however, when it comes to native, i.e. non-hydrolysed collagen. This type of collagen is much larger (over 300 kDa), since it is not decomposed, and its mechanism of action is different and the beneficial effects on skin and cartilage are proven by clinical studies. Only smaller particles have actually an effect in hydrolysed collagen, whereas in native collagen size does not matter, since it is not decomposed.
Why would collagen have an effect on hair and nails, if they do not contain collagen, but keratin?
Hair and nails are not made of collagen; however, they grow out of the skin, which does contain collagen. Consuming collagen will not impact the structure of your hair and nails, but will affect the firmness at the point of growth, which clinical studies have shown to produce a lusher and firmer scalp; it will also reduce hair loss and improve the nail firmness and decrease nail brittleness.
Frequently asked customer questions
Does collagen aid in getting rid of atopic dermatitis?
Can I use Kolagen Q+ instead of Kolagen lift in liquid when travelling?
Why does the liquid contain preservatives?
Liquids containing plenty of water are more susceptible to microbiological deterioration; consequently the preservatives in this product are necessary. All the dietary supplements in the liquid contain one type of preservative in order to last through the entire shelf life. The most frequently used preservatives in liquid are sorbic and benzoic acid salts. Both are also present in natural substances. Benzoic acid, for example, is naturally present in smaller quantities in most fruits, mushrooms, cinnamon and fermented dairy products, and in larger quantities it can be found in some berry varieties, mainly cranberries and blueberries. It prevents the growth and propagation of mould and yeast and of some types of pathogen bacteria. With the purpose of preventing any microbiological deterioration, it is also added to Kolagen lift in liquid. With a single daily dose of Kolagen lift you consume as many benzoic acid as from 50 g of cranberries.
Of course, any substance can be hazardous if consumed in excessive quantities. The recommended daily dose is 20 ml of Kolagen lift and this liquid contains a truly small quantity of the mentioned preservatives, therefore it is not in any way harmful to health and does not represent a risk for consumers. However, we always recommend that when taking dietary supplements you follow the recommended daily quantity and the general principles of a healthy diet.
Can I take Kolagen Q+ together with ceramides?
Yes. Kolagen Q+ in capsules and ceramides have added zinc. The acceptable upper threshold for zinc is 25 mg/day (from all sources, even from food). By simultaneously taking Kolagen Q+ and ceramides you consume 15 mg of zinc per day, and with a healthy diet you consume 10 mg on average per day. This totals 25 mg, which is the upper threshold. For long-term consumption we would however recommend combining ceramides with Kolagen lift products.
Do recreational athletes have to add collagen?
Athletes additionally burden their joints with their activity, which is why they should consider preventively adding collagen, which aids in building and repairing muscles, tendons, ligaments and cartilage, which are most exposed during exercise. An excellent choice for recreational athletes would be Kolagen Flex.
Can I take Kolagen Q+ or Kolagen lift in liquid during pregnancy?
Before starting to take any dietary supplements that are not directly intended for pregnant women, we recommend that you consult your physician or gynaecologist. We recommend Kolagen in powder with added vitamin C to pregnant women, since it does not contain preservatives and other added vitamins. However, both new Medex collagen products are safe for use during pregnancy and breastfeeding
Which collagen should I choose in order to improve the changes of ageing?
How long do I have to take collagen?
We recommend at least 60 to 90 days of regular use. After which you may stop taking collagen for a shorter period of time, a month or two, and then resume, since the effects wane with time.
What do I have to add to collagen in order to improve absorption?
The collagen and elastin in the Kolagenlift liquid contain small particles with low molecular mass which are perfectly absorbed into the body (collagen in the size of 2 kDa and elastin 1.4 kDa). Studies on the effectiveness of hydrolysed collagen have shown that particles of hydrolysed collagen have excellent absorption properties and pass through the intestinal wall and into the circulatory system partly intact, and stimulate the synthesis of own collagen.
Is collagen of fish origin more effective than collagen of bovine origin?
No. Collagen is obtained mostly from bovine hide or fish skin. Collagen is a universal molecule present in all animals in a very similar amino acid composition, since it always has a similar role, i.e. tissue elasticity and flexibility. Absorption does not depend on the source of collagen, but rather on the size of molecules. Collagen in dietary supplements, which stimulate the formation of collagen in the body, is separated by its amino acid composition, quality of collagen peptides and their molecule mass.
Is collagen with added vitamins of poor quality?
No. If vitamins are added to collagen in appropriate daily doses, which additionally stimulate the formation of collagen or in a different way affect the quality of nails, hair, or skin, this is value added to the product. On the other hand, if the product does not contain vitamins, this does not represent a disadvantage. The most important thing is that collagen that you take has proven effects per the recommended daily dose, which are also confirmed by studies.
What is the difference between elastin and collagen?
Collagen and elastin are proteins produced by a cell named fibroblast in the papillary dermis (deeper skin layer). Together, they give strength, structure and support to our skin. Collagen gives strength to skin; it is however elastin the one that enables skin to return to its form when we make certain facial expressions and grimaces. Elastin ensures skin’s elasticity, flexibility and firmness, while collagen gives it its fullness, provides hydration and smoothness. This is why these two proteins go hand in hand. Elastin gives skin its ability to stretch and, more importantly, to always return to its form.
Kolagen Lift 300ml includes 5000 mg of collagen in daily dose, while Kolagen Q+ this just 66 mg? Is not it too low for reaching the promised results?
Kolagen Q+ capsules contain different type of collagen than Kolagen Lift 300ml. This one is called native or undenatured collagen. It is not hydrolyzed, but present as an intact 3D structured molecule (hydrolyzed is not in intact structure but degraded into tiny particles with very low molecular mass) . Its mechanism of action is completely different from hydrolyzed collagen. When ingested, it travels to the gut, where immune receptor cells of the GALT system in the intestinal wall recognize it and decrease production of immune effector cells that react to our own collagen, which usually the case in inflammatory autoimmune disorders of collagenous tissues (as for example in osteoarthritis). This mechanism is known as the oral tolerance and results in decreased degradation of own collagen. Clinical studies have confirmed daily doses as low as 0,5 mg up to 40 mg to be effective in improving skin status and joint health.
If you are still not sure which collagen is suitable for you or in case you have any additional questions, we are always available on all our digital channels and contacts.
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